近期,美国血管外科协会陆续在《Journal of Vascular Surgery》杂志上就腹主动脉瘤治疗中的几个令人关注的问题给出了他们的建议,并且提出了一些争议点以及未来的方向,小编将为大家一一呈现。
Society for Vascular Surgery implementationof guidelines in abdominal aortic aneurysms: preoperative surveillance and threshold for repair
Rae S. Rokosh, Winona W. Wu, Mark K.Eskandari, and Elliot L. Chaikof1. 无症状的真性腹主动脉瘤的干预仍依据超声,CTA或MRI上测量到的主动脉最大外径:
推荐在垂直于CTA三维重建中心线的横断面上进行直径测量
CT横断面上短轴的距离最接近最大瘤体直径[1]
2. 直径<4.0cm的无症状真性AAA每年破裂的风险几乎可以忽略不计;3. Cochrane上一项对UKSAT (UK small aneurysm trial),ADAM (aneurysm detection and management study),CAESAR (comparison of surveillance vs aortic endografting for small aneurysm repair)和PIVOTAL (positive impact of endovascular options for treating aneurysm early)研究的分析显示无症状小AAA(4.0-5.4cm)立即进行干预的获益不明显[2]4. 普遍认为,对于女性最大径达到5cm,对于男性最大径达到5.5cm时,AAA年破裂的风险超过择期手术相关的围手术期风险;5. 根据AAA直径估计的年破裂风险如下表[3,4](女性患者适用性较差):
引用文献: 1. Chaikof EL, Blankensteijn JD, Harris PL,White GH, Zarins CK, Bernhard VM, et al. Reporting standards for endovascularaortic aneurysm repair. J Vasc Surg 2002;35:1048-60.2. Ulug P, Powell JT, Martinez MA, BallardDJ, Filardo G. Surgery for small asymptomatic abdominal aortic aneurysms.Cochrane Database Syst Rev 2020;7:CD001835.3. Parkinson F, Ferguson S, Lewis P,Williams IM, Twine CP; South East Wales Vascular Network. Rupture rates ofuntreated large abdominal aortic aneurysms in patients unfit for electiverepair. J Vasc Surg 2015;61:1606-12.4. Powell JT, Gotensparre SM, Sweeting MJ,Brown LC, Fowkes FG, Thompson SG. Rupture rates of small abdominal aorticaneurysms: a systematic review of the literature. Eur J Vasc Endovasc Surg2011;41: 2-10.5. Chaikof EL, Dalman RL, Eskandari MK,Jackson BM, Lee WA, Mansour MA, et al. The Society for Vascular Surgerypractice guidelines on the care of patients with an abdominal aortic aneurysm.J Vasc Surg 2018;67:2-77.e72.6. Vorp DA, Vande Geest JP. Biomechanicaldeterminants of abdominal aortic aneurysm rupture. Arterioscler Thromb VascBiol 2005;25: 1558-66.7. Lo RC, Lu B, Fokkema MT, Conrad M, Patel VI,Fillinger M, et al. Relative importance of aneurysm diameter and body size forpredicting abdominal aortic aneurysm rupture in men and women. J Vasc Surg 2014;59:1209-16.
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